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Cerebellar Ataxia With Anti-Glutamic Acid Decarboxylase Antibodies
Arch Neurol 58:225-230, Honorat,J.,et al, 2001
See this aricle in Pubmed

Article Abstract
Antibodies to glutamic acid decarboxylase (GAD-Ab) are described in patients with insulin-dependent (type 1) diabetes mellitus (IDDM), in stiff-man syndrome, and, recently, in a few patients with cerebellar ataxia. These results suggest a l ink between high level of GAD-Ab and some cases of cerebellar ataxia, particularly women with IDDM. If high serum levels of GAD-Ab are detected, the cerebrospinal fluid should be evaluated for the presence of oligoclonal IgG bands and intrathecal synthes is of GAD-Ab to further prove an autoimmune origin of the syndrome.
 
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ataxia
ataxia,cerebellar
ataxic gait
autoimmune cerebellar ataxia
autoimmune disease
cerebellar ataxia,primary
cerebellar atrophy,primary
cerebrospinal fluid,abnormal
cerebrospinal fluid,oligoclonal IgG in
diabetes mellitus
dysarthria
glutamic acid decarboxylase,antibody
MRI
MRI,abnormal
MRI,negative
nystagmus

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